SureGuide Offerings Include GeCKO Libraries and Full Customization for Any CRISPR Screening Experiment

SANTA CLARA, Calif., Oct. 20, 2016

The Agilent 4200 TapeStation system offers automated sample processing for quick and reliable sample quality control within any Next Generation Sequencing (NGS), microarray (aCGH) or quantitative PCR (qPCR) workflow.

• Automated - Unattended walk away operation with fully automated sample processing for up to 96 samples.
• Scalable - Individual channels facilitate variable throughput from 1 - 96 samples at a constant cost..
• Flexible - Ready-to-use ScreenTape technology enable easy switching between DNA and RNA assays. Sample can be provided in either 16-tube strips or 96 well plates.
• Fast - Simplify your workflow without any system set up procedures and obtain reliable results in as little as 1-2 minutes per sample, even for 96 samples.

miRNAs (microRNAs) are small single-stranded non-coding RNAs (19-30 nucleotides long) that play a widespread role in post-transcriptional gene silencing. Agilent miRNA microarrays provide unmatched performance in high throughput miRNA profiling.

Recently tested in the miRQC study¹, Agilent SurePrint miRNA Microarrays exhibited performance superior to qPCR, sequencing, and other microarray platforms for consistent miRNA detection by showing the highest titration response, reproducibility, and precision in accuracy.

Now updated to release 21, Agilent miRNA microarrays are available pre-designed for human, mouse, and rat species. Or, design your custom microarray to have any or all available miRNA target probes. The latest miRBase database release 21 has a total of 28,645 entries in 223 species, an increase of 4,196 new hairpin sequences from release 20.

Better content

• Latest miRBase 21 content
• Pre-designed microarrays available for human, mouse, and rat species

Better flexibility

• Customizable microarray design to target any set of miRNA probes in multiple array formats and spot diameters
• Create multi-species miRNA microarrays – all 223 species available from miRBase 21

Better performance

• Highest titration response, reproducibility, and precision in accuracy
• High sensitivity with a dynamic range up to 6 orders of magnitude using only 100 ng of total RNA

The SureSelect Human All Exon V6 is a high performing design that targets updated content, including challenging regions, from the databases relevant to both the clinical and translational researchers. Optimized bait selection and boosting enables highly uniform coverage of the exome and each individual targeted exon. This improvement helps address the current observation of the inverse correlation between depth of coverage and breadth of coverage providing balanced coverage, maximizing variant information output for per exome sequenced.